Bovine mastitis, the most significant disease of dairy herds. It has a huge effect on dairy farming economics due to the reduction in milk production and treatment cost. The severity of this problem can be classify into subclinical, clinical and chronic form and its degree is dependent on the nature of the causative pathogen, age of animal, immunological status, health status and lactation status of the animal. Subclinical mastitis is difficult to detect due to absence of any visible indications. Chronic mastitis is a rarer form of the disease but result in persistent inflammation of the mammary gland. Therapeutic success of mastitis depends mainly on accurate diagnosis, severity of udder pathology, drug selection, and relevance of route of administration, supportive treatment and elimination of predisposing factors (Hossain et al., 2017). This review will highlights the key antibiotics for treatment of clinical and subclinical mastitis as a prospective approach for control of mastitis in dairy animals.
