Impetigo continues to be an important paediatric skin infection. Staphylococcus aureus is the commonest bacteria associated with Impetigo. Drug resistance particularly to first line oral antibiotics is alarmingly high in Staphylococcus aureus. This study aims to find the bacterial isolates causing impetigo and their susceptibility pattern to drugs particularly Mupirocin. This prospective study was done in patients presenting with impetigo to the dermatology OP of a tertiary care hospital for the period of six months from May 2017 to October 2017. All the samples were collected aseptically with two sterile cotton swabs for each sample from the lesion, which were processed for isolation and identification of bacterial pathogens, according to the standard microbiological techniques. The prevalence was common in the Paediatric age group. Scabies was commonly associated with impetigo in 13%. Staphylococcus aureus was the cause in 63 % of impetigo followed by Streptococcus pyogenes in 3% of patients. Streptococcus pyogenes strains still remain susceptible to all the common antibiotics. Methicillin resistant Staphylococcus aureus (MRSA) was found in of the 63 Staphylococcus aureus strains. The prevalence of High level Mupirocin in the community was 0% and Low level Mupirocin resistance was . Mupirocin is one of the commonest drugs used for topical use in Impetigo and is effective against both staphylococcus and streptococcus and not effective against the normal cutaneous flora. Mupirocin is also used to eradicate nasal and cutaneous carriage of Staphylococcus aureus. | A study of bacterial isolates from impetigo and their resistance pattern to Mupirocin
