A field experiment was carried out to study the bio-efficacy of zinc fortified SSP on growth and yield of soybean at Regional Research Centre, Dr. Panjabrao Deshmukh Krishi Vidyapeeth, Amravati, Mahrashtra during kharif season of the year 2016. A set of six treatments regular SSP, Zincated SSP, regular SSP + recommended dose of zinc sulphate (Zn 21%) as soil application, zincated SSP + 1 foliar spray of zinc sulphate (Zn 21%), Zincated SSP + 2 foliar spray of zinc sulphate (Zn 21%) and regular SSP + 2 foliar spray of zinc sulphate (Zn 21%) were taken under Randomized Block Design with four replication to evaluate bio-efficacy of zinc fortified SSP in soybean. The experimental results revealed that application of treatment zincated SSP + 1 foliar spray of zinc sulphate (Zn 21%) was recorded significantly highest seed yield (2137 kg/ha) over treatment regular SSP (1887 kg/ha) but found at par with zincated SSP, regular SSP + recommended dose of zinc sulphate (Zn 21%) as soil application, and zincated SSP + 2 foliar spray of zinc sulphate (Zn 21%). Similar trend was also observed in respect of straw yield. Treatment zincated SSP, regular SSP + recommended dose of zinc sulphate (Zn 21%) as soil application, zincated SSP + 1 foliar spray of zinc sulphate (Zn21%) and zincated SSP + 2 foliar spray of zinc sulphate (Zn21%) recorded significantly higher GMR over regular SSP whereas in case of B:C ratio regular SSP + recommended dose of zinc sulphate (Zn 21%) as soil application recorded highest B:C ratio followed by treatment zincated SSP, zincated SSP + 1 foliar spray of zinc sulphate (Zn 21%) and zincated SSP + 2 foliar spray of zinc sulphate (Zn 21%).