In this study, 46 strains of actinomycetes were isolated from 40 samples including: sediments, sponges, soft corals, echinoderms and starfish collected from three coastal areas of Vietnam: Thanh Hoa – Quang Binh – Quang Tri. The strains were fermented in A+ medium and fermentation broths were extracted 5 times with ethyl acetate then the extracts were evaporated under reduced pressure to yield crude extracts. | Identification and antimicrobial activity of actinomycetes strains isolated from marine samples in the coastal area of Thanh Hoa – Quang Binh – Quang Tri