Bloodstream infections are frequent and life – threatening, can lead to increase in morbidity, mortality and health care cost of patients admitted in intensive care unit (ICU). In addition to this, infections due to emerging multidrug resistant (MDR) microorganisms, the treatment becomes challenging. With the rising problem of drug resistance, the present study was undertaken to evaluate the most prevalent bacterial pathogen causing Bloodstream infections in adult patients admitted to an Intensive Care Unit (ICU) with their antimicrobial sensitivity pattern. A retrospective analysis of data was done on the blood cultures received from 817 patients with clinically suspected bloodstream infections, admitted in Medical ICU of tertiary care hospital, Navi Mumbai, between October 2016 and October 2018. All the samples were received and processed in the Department of Microbiology, using standard microbiological techniques and antimicrobial sensitivity was done according to CLSI guidelines. | Bacteriological profile and antibiogram of isolates from bloodstream infections in patients admitted in ICU from a Tertiary care hospital, Nerul, Navi Mumbai, India