Plants are constantly exposed to biotic stresses, which cause changes in plant metabolism including physiological damages, leading to crop productivity losses. This study was conducted to investigate bio-fertilizer applications (., phosphorein, microbein, and combination of them at a ratio of 1:1 for seed before sowing) influences on two varieties (., Giza 429 and Giza 40) of Vicia faba (L.) plant performances on borne diseasesinfected soil. Growth, yield and its quality, physio-biochemical attributes, nutrient contents and disease assessment were investigated. Combined phosphorein and microbein treatment significantly increased all plant growth characteristics, leaf photosynthetic pigments, all physio-biochemical attributes, and nutrients contents compared to individual phosphorein or microbein application, which in turn significantly exceeded the control (seed without bio-fertilizers). | Integrative application of phosphorein and microbein improves vicia faba (L.) performance and controls soil-borne diseases