The term ‘Vibriocin’ is specifically indicates the bacteriocin of Vibrio species. The present study reports the screening Vibriocin producing marine bacteria for food and aquaculture application. Out of 40 strains from Clam (Meretrix meretrix) species, screened against eight seafood borne pathogens, two Vibriocin producing bacteria were active against Staphylococcus aureus. Crude Vibriocin of these two isolates were subjected to salting-out for partial purification and exposed to different conditions ., pH, temperature and detergent for its antibacterial activity. | Characterization of vibriocin and prospect of co-culture method to overcome the diminishing antibacterial activity
