The rate of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) has been steadily increasing in developing countries like India. The availability of rapid and reliable methods for the detection of drug resistance to second-line drugs is vital for adequate patient management. MTBDRsl-2 is newer DNA based test recommended by WHO for screening of XDR and Pre XDR is a rapid, screening method that detects genetic mutation responsible for resistance in second line injectable drugs in tuberculous patients mainly against Flouroquinolones and /or second line injectable drugs. | Detection of pre-extensively drug resistance (PRE-XDR TB) and extensively drug resistance (XDR-TB) among pulmonary multidrug resistant tuberculosis (MDR-TB) patient by line probe assay
