Among the genus, Selaginella rolandi-principis Alston was first recorded in 1934 9. In Vietnam, Selaginella is found growing on rocks and/or sandy arid land along the country at an elevation of less than 1000 m above sea level. Among thirty nine recognized species, thirteen of them are common appearance including S. rolandi-principis. The plant has been used in Vietnamese folk medicine to treat acute hepatitis, cholecystitis, inflammation, dysentery, pulmonary tuberculosis and hyperglycemia. In this study, we report the isolation and evaluation of antidiabetic activity of isolated compounds from S. rolandi-principis. | Triterpenoid from selaginella rolandi-principis and their PTP1B inhibitory activity