Two dogs of 2 and 3 month old were presented with history of lethargy, vomition and foul smelling diarrhea. The dogs were febrile, dehydrated, mucous membrane were pale and pinkish. Both the dogs were sent for haematological examination and revealed microcytic and hypochromic anemia. Both the dogs were tested for canine parvo virus through ELISA. Serum sample of one dog was sent for modified Elisa (immunocomb) test and it tested S2 positive. Faeces of the other dog were sent for immune chromatographic qualitative test and showed reaction.