The present study was undertaken to ascertain the presence of anticancer phyto-constituent in the Indian Combretum species and its further utilization in the treatment of tumor. The phyto-chemical constituents of the leaf and bark extracts were recognized with reference to standard on the same HPTLC plate. The leaf extracts exhibited higher quantity of combretastatins than the bark samples. The combretastatin content was recorded the highest (182 µg/g) in the leaf extract of C. albidum. Antibacterial activity was studied by disk diffusion assay against seven bacterial strains. | Quantification, antibacterial assay and cytotoxic effect of Combretastatin, an anticancer compound from three Indian Combretum species