Pulmonary fungal infections are common potentially life-threatening conditions in immuno-compromised patients. Diagnosis represents a challenge due to the non-specific clinical manifestations. Empirical use of anti-fungal drug therapy has been a burden for years due to high cost and drug toxicity. This study was designed to determine the presence of Candida chest infection in immuno-compromised patients in Tanta University Hospitals. A total of 150 patients with chest infection were selected during the period from June 2015 till June 2017. Collected samples were cultured on Sabouraud's Dextrose agar media. Candida isolates were tested using integral system yeast plus (ISYP) for yeast typing and antifungal susceptibility. | Identification of candida species isolated from egyptians patients with chest infection using integral system yeast plus