Chapter 11 introduce to cell communication. This chapter presents the following content: External signals are converted to responses within the cell; reception: a signal molecule binds to a receptor protein, causing it to change shape; transduction: cascades of molecular interactions relay signals from receptors to target molecules in the cell;. | Lecture Biology (7th edition) - Chapter 11: Cell communication Chapter 11 Cell Communication PowerPoint Lectures for Biology, Seventh Edition Neil Campbell and Jane Reece Lectures by Chris Romero Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings • Overview: The Cellular Internet • Cell-to-cell communication – Is absolutely essential for multicellular organisms Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings • Biologists – Have discovered some universal mechanisms of cellular regulation Figure Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings • Concept : External signals are converted into responses within the cell Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Evolution of Cell Signaling • Yeast cells – Identify their mates by cell signaling 1 Exchange of factor mating factors. Receptor Each cell type secretes a mating factor a that binds to receptors on the other cell type. Yeast cell, factor Yeast cell, mating type a mating type 2 Mating. Binding of the factors to receptors induces changes a in the cells that lead to their fusion. 3 New a/ cell. The nucleus of the fused cell includes all the a/ genes from the Figure a and a cells. Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings • Signal transduction pathways – Convert signals on a cell’s surface into cellular responses – Are similar in microbes and mammals, suggesting an early origin Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Local and LongDistance Signaling • Cells in a multicellular organism – Communicate via chemical messengers Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings • Animal and plant cells – Have cell junctions that directly connect the cytoplasm of adjacent cells Plasma membranes Gap .