Several studies have reported that daptomycin induced artificial prolongation of prothrombin time (PT) in some test reagents, particularly in warfarin users. However, it remains unknown whether the artificial prolongation can be affected by coagulation abnormalities other than the use of warfarin. | Dose-dependent effect of daptomycin on the artificial prolongation of prothrombin time in coagulation abnormalities: In vitro verification