Cadmium (Cd) is a well known environmental and industrial toxicant causing damaging effects in numerous organs. In this study, we examined the role of heme oxygenase-1 (HO-1) in modulating the Cd-induced apoptosis in human hepatoma (HepG2) cells after 24 h exposure. | Heme oxygenase-1 attenuates cadmiuminduced mitochondrial-caspase 3- dependent apoptosis in human hepatoma cell line