A series of experiments were carried out with different combinations of various growth factors and hormones like Growth Hormone (GH), Insulin like Growth Factor-I (IGF-I), Epidermal Growth Factor (EGF), Thyroxin (T4) and Follicle Stimulating Hormone (FSH) in culture medium to support growth and development of goat preantral follicles (PFs) (diameter ranging from 150-400µ) in vitro for a period of eight days and the retrieved oocytes from cultured preantral follicles were kept for incubation in in vitro maturation media (IVM) for 27 hours. | Effect of different combinations of the growth factors and hormones on invitro maturation of goat preantral follicles