Vaccination is the best method for controlling the disease and the protection of the livestock. During the vaccination, most of the animals get stressed which will influence the development of the immunity against the vaccination. The present study was conducted to evaluate the herbal anti-stressor product (Restobal® , M/s Ayurvet Limited) against the management of vaccination stress in buffaloes. Buffaloes in treatment group administered with herbal anti stressors (Restobal) showed the significant changes by elevation of the glutathione peroxidase levels, total leukocyte and lymphocyte count and reduced cortisol levels when compared with the buffaloes in control group. It is observed that herbal anti stressor product (Restobal) can be recommended as a supportive therapy during the vaccination programmes in buffaloes. | Evaluation of herbal anti-stressor product Restobal during the vaccination stress in buffaloes