Fexofenadine is an important medicament having significant antihistaminic activity. It is currently being prepared by chemical route which is in numerous stages of development with a yield of less than 10%. In this study, bio-transformation of terfenadine to fexofenadine was investigated using few microbial strains. Among the microbes studied, Absidia corymbifera ATCC14058 showed the highest conversion efficiency in a base line study. | Biotransformation of terfenadine to fexofenadine by absidia corymbifera ATCC 14058