The present study was intended to delineate the Anti Helminthis and Molluscicidal activity of Momordica dioica fruit extract. The crude extract was obtained by the employment of Soxhlet extraction method. The extract was used to screen the antagonistic activity in vitro by taking Pheretima posthumous and Indoplanorbis exustus as the study subjects. The results obtained proved the capability of extract to downregulate the biological activities of subjects. Mortality was induced by varying concentrations (100-1000 ppm/ml). Interestingly the antagonistic activity was in direct proportional with the extract administrated. | Anti helminthis and molluscicidal activity of momordica dioica against pheretima posthumous and indoplanorbis exustus