The present study reveals the robust and facile methodology for the synthesis of massively selective dispiro-3-phe‑ nylpyrrolothiazole hybrids via one-pot 1,3-dipolar cycloaddition reaction by environmentally supported solvents and to evaluate their biological activities. | An expeditious and environmentally benign synthesis of dispiro-3-phenylpyrrolothiazoles in ACI EG eutectic mixture and its antioxidant and antimicrobial activities against urinary tract pathogens