4-Thiazolidinone ring is reported to have almost all types of biological activities. Also, it present in many marketed drugs. An unexpected synthesis of (Z)-ethyl 2-((Z)-5-((dimethylamino)methylene)-4-oxo-3-phenylthiazolidin2-ylidene)acetate via deacetylation mechanism. | A novel synthesis X-ray analysis and computational studies of Z -ethyl 2- Z -5- dimethylamino methylene - 4-oxo-3-phenylthiazolidin-2-ylidene acetate as a potential anticancer agent