The dynamic changes of secondary metabolites and tyrosinase activity of Malus pumila fowers were investigated during blooming for full use of M. pumila fowers. Phloridzin, astragalin and afzelia were selected as the indicators to determine the optimum extraction conditions of M. pumila flowers by HPLC analysis and three-factor and three-level orthogonal design experiments. | Dynamic changes of secondary metabolites and tyrosinase activity of Malus pumila flowers