In the present study, a series of new hydrazone and sulfonamide derivatives of 1,2,4-triazole were synthesized. Initially three 4-substituted-5-(2-pyridyl)-1,2,4-triazole-3-thiones ZE-1(a–c) were treated with ethyl chloroacetate to get the corresponding thioesters ZE-2(a–c), which were reacted with hydrazine hydrate to the respective hydrazides ZE-3(a– c). | Synthesis characterization molecular docking evaluation antiplatelet and anticoagulant actions of 1 2 4 triazole hydrazone and sulphonamide novel derivatives
