This paper explains a statistical method that measures the reliability rate of each part in the system as well as the entire supply chain. Moreover, the paper elucidates a mathematical model that improves the reliability of the supply chain through minimization of cost components. | Effective cost minimization strategy and an optimization model of a reliable global supply chain system Uncertain Supply Chain Management 7 2019 381 398 Contents lists available at GrowingScience Uncertain Supply Chain Management homepage uscm Effective cost minimization strategy and an optimization model of a reliable global supply chain system Yahya H. Daehya Krishna K. Krishnana Ahmed K. Alsaadia and Saleh Y Alghamdia a Wichita State University United States CHRONICLE ABSTRACT Article history Attributable to high competition in global manufacturing market and outsourcing suppliers Received November 2 2018 many supply chain systems have become more complex and faced with high risks and low Received in revised format performance. Many financial losses and failures are likely to be due to risks among supply November 18 2018 chain s components. As a prescription to improve quality performance and profitability of the Accepted December 21 2018 Available online supply chain companies would like to measure and optimize the reliability of the entire supply December 24 2018 chain system. Also companies are interested in minimizing the cost of processes and Keywords improvement throughout the supply chain system. This paper explains a statistical method that Supply chain system measures the reliability rate of each part in the system as well as the entire supply chain. Reliability optimization Moreover the paper elucidates a mathematical model that improves the reliability of the supply Minimum cost chain through minimization of cost components. The results and findings of this study confirm Reliability rate that the proposed model can be applied to improve the supply chain system. Also the system can be improved to reach a designed reliability rate as given target to the model. The illustrated methodology can be used as a guide on how to develop a reliable supply chain system plan with low possible costs. 2019 by the authors licensee Growing .