Staphylococcus aureus is very well adapted to colonise the human skin and produce a asymptomatic carrier state. Colonization with antibiotic resistant S. aureus represents both a risk factor for the colonized individual and their immediate contacts. This research study was carried out to investigate the prevalence of multidrug resistant Staphylococcus aureus carriers in and around Trivandrum. A total of 2361 samples were collected from healthy asymptomatic adults to isolate MRSA. | Community reservoir of multidrug resistant Staphylococcus aureus in and around trivandrum