Isocitrate dehydrogenase 1/2 (IDH1/2), BAP1, ARID1A and PBRM1 have been reported as the most frequent mutant genes in intrahepatic cholangiocarcinoma (ICC), and their relationships with clinicopathological features and prognosis were researched in this study. | Distinct clinical and prognostic implication of IDH1 2 mutation and other most frequent mutations in large duct and small duct subtypes of intrahepatic cholangiocarcinoma