Transgenesis refers to the technique involving the manipulation of genes of one organism and deliberate addition into the genome of another organism of same or other species and sometimes specific inhibition of endogenous gene inhibition. Transgenesis promises to solve different problems. The animals produced through the process of transgenesis will serve us various purposes from medicinal to commercial uses. Different methods of producing transgenic animals are available; however, their effectiveness varies with species involved. Various kinds of transgenic animals have been produced to date. However, few issues related to ethics and regulations of transgenic animals remain to be addressed. In this review, we tried to cover the basics of transgenics to understand their promise in the livestock world. | Transgenesis in animals Principles and applications A review