It remains controversial whether weight change could influence the risks of colorectal cancer (CRC) and mortality. This study aimed to quantify the associations between full-spectrum changes in body mass index (BMI) and the risks of colorectal cancer (CRC) incidence, cancer-related and all-cause mortality among midlife to elder population. | Longitudinal associations between BMI change and the risks of colorectal cancer incidence cancer-relate and all-cause mortality among 81 388 older adults