The majority of patients with head and neck squamous cell carcinoma (HNSCC) receive bilateral elective nodal irradiation (ENI), in order to reduce the risk of regional failure. Bilateral ENI, as compared to unilateral ENI, is associated with higher incidence of acute and late radiation-induced toxicity with subsequent deterioration of quality of life. | Mapping of sentinel lymph node drainage using SPECT CT to tailor elective nodal irradiation in head and neck cancer patients SUSPECT-2 A single-center prospective trial