Antibacterial activities of Black pepper fruit extract were studied against some bacterial strains as- Pseudomonas fluorescens, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus vulgaris, and Bacillus subtilis. The black pepper fruit extracts were prepared in four organic solvents as methanol, ethyl acetate, chloroform and benzene. Effectiveness against bacterial strains showed by all extract (which prepared by organic solvent) but the benzene extract showed the maximum growth inhibition against Klebsiella pneumoniae bacteria at 100µl/ml extract concentration. It is also resistance for some antibiotics as Lincomycin and Oleandomycin. The present study depict that the black pepper fruit extract showed good antibacterial activity. | Black pepper Piper nigrum fruit extract activity against some pathogenic bacterial strains by disc diffusion method