Surgical site infections pose a major threat to the morbidity of immunosuppressed patients. They lead to increased hospital stay, delayed recovery, increased treatment cost and a high risk of spread of Nosocomial infections. The present study was conducted to identify the post-operative wound infection rate, to isolate and identify the bacterial pathogens and to determine its antibiotic susceptibility pattern. Total 70 pus samples were collected from patients having post-operative wound infections out of 716 operations performed during January to December, 2016. | Surveillance of post-operative wound infections along with their bacteriological profile and antibiotic sensitivity pattern at government cancer hospital Aurangabad India