Seroma formation is a common complication after mastectomy and is associated with delayed wound healing, infection, skin flap necrosis, patient discomfort and repeated visits to the out patient clinic to deal with seroma and its sequelae. | A multi-center double blind randomized controlled trial evaluating flap fixation after mastectomy using sutures or tissue glue versus conventional closure Protocol for the Seroma reduction After Mastectomy SAM trial