Các cây thuốc chống viêm như Kim Ngân, Núc Nác đã được nhân dân ta sử dụng từ lâu. Việc nghiên cứu tác dụng chống viêm của Hoa cây Kim Ngân kết hợp với Núc Nác gợi ý một hướng nghiên cứu mới về thuốc điều trị chống viêm, với mong muốn tác dụng chống viêm mạnh hơn, tốt hơn, không có phản ứng có hại không mong muốn. | Nghiên cứu tác dụng chống viêm của hoa cây Kim Ngân Lonicera japonica Thunb. Caprifoliaceae kết hợp với Núc Nác Oroxylum indicum Vent. Bignoniaceae VNU Journal of Science Medical and Pharmaceutical Sciences Vol. 36 No. 2 2020 27-34 Original Article The Anti-inflammatory Effect of Honeysuckle Flowers Lonicera japonica Thunb. Caprifoliaceae in Combination with Oroxylum Indicum Oroxylum indicum Vent. Bignoniaceae Le Thi Diem Hong1 Pham Thi Van Anh2 Nguyen Thi Thanh Loan2 Do Hong Ngoc1 3 VNU School of Medicine and Pharmacy Vietnam National University Hanoi 144 Xuan Thuy Cau Giay Hanoi Vietnam 2 Hanoi Medical University 1 Ton That Tung Dong Da Hanoi Vietnam Received 16 March 2020 Revised 17 April 2020 Accepted 20 June 2020 Abstract This study investigates the anti-inflammatory effect of the honeysuckle flower in combination with Oroxylum indicum in search of a new kind of anti-inflammatory therapy drugs with stronger anti-inflammatory effects and without unwanted adverse reactions. The study results show that a honeysuckle flower dose of g kg day Oroxylum indicum dose of g kg day together with honeysuckle flower combined with Oroxylum indicum with 1 1 ratio had an acute anti- inflammatory effect on the white rat on a mouse Leg Edema Model with carrageenin and the model causing mouse peritonitis. The results also show that a honeysuckle flower dose of g kg day Oroxylum indicum the dose of g kg day together with honeysuckle flower combined with Oroxylum indicum with 1 1 ratio had a chronic anti-inflammation effect on the white mouse on the model causing chronic inflammation of the granuloma. These results open up a subsequent research direction on the possibility of combining various anti-inflammatory medicinal herbs to obtain better anti-inflammatory efficacy and contribute to the promoting of the effect of the available domestic medicinal resources. Keywords Honeysuckle flowers Oroxylum indicum anti-inflammatory effect. Corresponding author.
