Although cases of multiple primary malignant neoplasms are increasing, reports of more than three or four primary metachronous malignant neoplasms are extremely rare. Moreover, very few publications have provided a genetic mutational analysis or have evaluated risk factors associated with such neoplasms. | Nine primary malignant neoplasmsinvolving the esophagus stomach colon rectum prostate and external ear canalwithout microsatellite instability A case report