The prognostic variability of thyroid carcinomas has led to the search for accurate biomarkers at the molecular level. Follicular thyroid carcinoma (FTC) is a typical example of differentiated thyroid carcinomas (DTC) in which challenges are faced in the differential diagnosis. | CRABP1 C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma and predict extrathyroidal extension