PTTG1-interacting protein (PTTG1IP/PBF) predicts breast cancer survival

PTTG1-interacting protein (PTTG1IP) is an oncogenic protein, which participates in metaphase-anaphase transition of the cell cycle through activation of securin (PTTG1). PTTG1IP promotes the shift of securin from the cell cytoplasm to the nucleus, allowing the interaction between separase and securin. PTTG1IP overexpression has been previously observed in malignant disease, . in breast carcinoma. | PTTG1-interacting protein PTTG1IP PBF predicts breast cancer survival

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