Succinate dehydrogenase deficiency in a PDGFRA mutated GIST

Most gastrointestinal stromal tumors (GISTs) harbor mutually exclusive gain of function mutations in the receptor tyrosine kinase (RTK) KIT (70–80%) or in the related receptor PDGFRA (~10%). | Succinate dehydrogenase deficiency in a PDGFRA mutated GIST

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