Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

Penetration of the mammary gland basement membrane by cancer cells is a crucial first step in tumor invasion. Using a mouse model of ductal carcinoma in situ, we previously found that inhibition of peptidylarginine deiminase 2 (PAD2, aka PADI2) activity appears to maintain basement membrane integrity in xenograft tumors. | Role of peptidylarginine deiminase 2 PAD2 in mammary carcinoma cell migration

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7    2    1    07-05-2021