Mannose-binding lectin (MBL) acts in the innate immune response to Helicobacter pylori. Interleukin 8 (IL-8) is a potent cytokine produced by gastric epithelial cells in response to H. pylori. | Combination of Helicobacter pylori infection and the interleukin 8 251 T A polymorphism but not the mannosebinding lectin 2 codon 54 G A polymorphism might be a risk factor of gastric cancer