The current study sought to investigate the anti-fatigue efficacy of poly herbal granule (PHG) formulations of the extracts of Asparagus racemosus, Chlorophytum borivilianum, Tinospora cordifolia, Tribulus terrestris and Withania somnifera enriched with general tonic and health promoting properties based on Aloe vera gel and soyabean whey in Swiss mice. The nutrient compositions of the selected PHG exhibited that the carbohydrates were the major constituents in both AVII and SBWII, followed by protein and total ash. Fat contents were and g100g-1 in AVII and SBWII, respectively. | Development of poly herbal granules and its anti-fatigue efficacy in Swiss mice