The Oyster mushroom (Pleurotus cystidiosus) was cultivated on different agrowastes as substrates such as; sugarcane bagasse (ScB), rice straw (RS), and wheat straw (WS), whereas the fourth formula composed of combination of these three substrates in a proportion of 1: 1. The ScB, RS and WS agro-wastes substrates were selected as the most favorable lignocellulosic sources. P. cystidiosus can efficiently degrade the agro-wastes and grow at wide range of temperatures. The effects of growing the Oyster mushroom on different lignocllulosic agro-wastes as substrates were tested through evaluating the levels of various parameters in the growing mycelium including: moisture contents, yield, total carbohydrates, crude fat, crude protein, crude fiber, ash, and minerals contents. | Effect of different agro-wastes substrates on the growth and productivity of the oyster mushroom in Upper Egypt