The phosphatase chronophin (CIN/PDXP) has been shown to be an important regulator of glioma cell migration and invasion. It has two known substrates: p-Ser3-cofilin, the phosphorylated form of the actin binding protein cofilin, and pyridoxal 5′-phosphate, the active form of vitamin B6. | Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under nonadherent serum-free conditions