Natural components of the plants, animals and mineral sources are used as medicines since ancient time as they have fewer or no side effects, plant products have been widely used in controlling cancer as complementary to synthetic medicine is gaining increased popularity. Present study was carried out with different extract of leaf, stem, root and the whole plant of Sida cordata (.) Borss (SC) to determine their probable anticancer/ antiproliferative effect on oral cancer using Human tongue squamous cell carcinoma (CAL-27) cell lines and normal human gingival fibroblast (HGF) cell lines in comparison with commonly used standard drug Cisplatin. | Effect of Sida cordata . borss extracts on oral cancer An invitro study