Bovine ocular squamous cell carcinoma also called cancer eye, represents the most economically important neoplasm in large animals. Hereditary factors, environmental factors (. latitude, altitude, exposure to sunlight), lack of eyelid pigmentation, age and dietary habits have all been reported to play a role in the etiopathogenesis of bovine ocular squamous cell carcinoma. Twenty four animals were subjected to surgical excision and autogenous vaccine was administered weekly once for four weeks. All the animals recovered completely with no recurrence for a follow up period of one year. | Management of bovine eye cancer with autogenous vaccine