The present study was aimed to prepare a conjugate of Fc fragment of mice IgG with rOMP 28 of Brucella melitensis and investigate its ability to influence the kinetics of humoral and cellular immune response in comparison to its unconjugated counterpart and the rOMP 28 alone in the mice model. | Immunological evaluation of FC receptor mediated antigen delivery of brucella melitensis recombinant outer membrane protein 28 Romp 28 in mice