Độc tố tương tự ciguatoxin trong mẫu cá thu ngàng Acanthocybium soladria tại Việt Nam

Bài viết công bố kết quả thực nghiệm phân tích độc tố ciguatoxin trong sản phẩm cá thu cắt khúc thu vào tháng 4/2019 có nguồn gốc từ vùng biển xa bờ Đông Nam Bộ Việt Nam; trình bày kết quả định danh các mẫu vật cá thu bằng kỹ thuật sinh học phân tử. | Độc tố tương tự ciguatoxin trong mẫu cá thu ngàng Acanthocybium soladria tại Việt Nam Vietnam Journal of Marine Science and Technology Vol. 19 No. 4A 2019 159 166 DOI https 1859-3097 19 4A 14611 https jmst Ciguatoxin-like toxin in mackerel Acanthocybium soladria in Vietnam Dao Viet Ha Phan Bao Vy Institute of Oceanography VAST Vietnam E-mail daovietha69@ Received 30 July 2019 Accepted 6 October 2019 2019 Vietnam Academy of Science and Technology VAST Abstract Two processed mackerel products were sent to VAST keylab on Food and Environmental Safety in Institute of Oceanography for Ciguatoxin criteria as exported seafood requirement. The specimens were caught from offshore region of Vietnam South-Eastern sea in April 2019. By DNA sequencing of COI gene both specimens were identified as Acanthocybium solandri one of high commercial mackerel species which is well-known to be distributed in Central and South-Eastern sea of Vietnam. In mouse bioassay both extracts from 2 samples exhibited acute toxicity which killed tested mice within 6 and 15 hours after . injection. In SIM LC MS-MS analysis the extracts showed the peak with retention time closed to that in CTX-1B standard in both cases of optimized and non-optimized solid phases. The result suggested that at least there was occurrence of CTX-like toxin in these mackerel specimens. The equivalent toxin levels were estimated as ng g and ng g 5 and 8 times higher than regulation limit for CTXs in seafood product ng CTX-1B g . Further verification is in progress to confirm toxin in these mackerel samples in Vietnam. However this data is the first alert on potential poisoning by consumption of mackerel not only in Vietnam but also in Asia. Keywords Mackerel ciguatera food poisoning Vietnam. Citation Dao Viet Ha Phan Bao Vy 2019. Ciguatoxin-like toxin in mackerel Acanthocybium soladria in Vietnam. Vietnam Journal of Marine Science and Technology 19 4A 159 .

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