The study reveals the possibility to use simultaneously botanicals and pesticide control products as efficient and environmental friendly for disease control, which could provide a decrease of the pesticide dose needed for plant protection. This experiment reports the in vitro compatibility of botanicals viz., Garcinia indica and Prosopis juliflora and pesticides Viz., Streptocycline, 2-bromo-2-nitropropane-1,3-diol,Carbendazim, Difenconazole, Hexaconazole, Propiconazol, Chlorothalonil, Copper oxychloride, Mancozeb, Chlorpyrifos, Dichlorovas and Dimethoate. Results indicate that, among the pesticides, 2- bromo-2-nitropropane-1,3-diol(bronopol) in combination with Prosopi sjuliflora and Garcinia indica recorded highest average zone of inhibition of and mm. Followed by Prosopis juliflora @1:5+Streptocycline 500ppm ( mm) and Garcinia indica @1:5+Streptocycline 500ppm ( mm). | In vitro compatibility between botanicals and pesticides against Xanthomonas axonopodis pv. punicae