A field experiment was carried out to evaluate the effect of sulphur and phosphorus application on yield and N, P and K contents of soybean grown on Vertisol. It was found that increasing application of sulphur and phosphorus, singly as well as in combination, significantly increased the grain yield and contents of N, P and K over control. The interaction of S x P exhibited a strong synergistic relationship in soybean nutrition grown on deficient soil. Result indicated that grain and straw yield, uptake of phosphorus and sulphur increased with increase in the rate of application of P and S individually as well as in various combinations. Applied various levels of P and S also influenced the quality parameters of soybean . protein content and oil content. Available P in soil increased with increasing levels of phosphorus. Similarly available S in the soil increased with increasing levels of sulphur. | Interaction effect of phosphorus and sulphur on yield and quality of soybean in a Vertisol