The present study was done to investigate the histopathological effect of the entomopathogenic fungi, Metarhizium anisopliae on Odontotermes obesus using Scanning Electron Microscopy (SEM). Adult worker termites were inoculated with 1x109 conidia/ml suspension of the fungi and maintained at 25±1°C temperature and 80 % relative humidity. SEM study showed that when this mitotic (asexual) spore (called conidia) of the fungus came into contact with the body of the termite, they germinated and the hyphae of the fungus that emerged penetrated the cuticle. | Scanning electron microscopy SEM study showed the mode action of Metarhizium anisopliae on Odontotermes obesus