Approximately 40% of colorectal cancer patients will develop colorectal liver metastases (CRLM). The most effective approach to increase long-term survival is CRLM complete resection. Unfortunately, only 10–15% of CRLM are initially considered resectable. | Treatment intensification with hepatic arterial infusion chemotherapy in patients with liver only colorectal metastases still unresectable after systemic induction chemotherapy a randomized phase II study - SULTAN UCGI 30 PRODIGE 53 NCT03164655 study protocol